1. Signaling Pathways
  2. Anti-infection
  3. Parasite

Parasite

Antiparasitics are a class of medications which are indicated for the treatment of parasitic diseases such as nematodes, cestodes, trematodes, and infectious protozoa.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-B0273R
    Sulfadiazine (Standard)
    Inhibitor
    Sulfadiazine (Standard) is the analytical standard of Sulfadiazine. This product is intended for research and analytical applications. Sulfadiazine is a sulfonamide antibiotic with antimalarial activity. Sulfadiazine can be used for toxoplasmosis research.
    Sulfadiazine (Standard)
  • HY-B2015R
    Carbosulfan (Standard)
    Inhibitor
    Carbosulfan (Standard) is the analytical standard of Carbosulfan. This product is intended for research and analytical applications.
    Carbosulfan (Standard)
  • HY-B0094S3
    Artemisinin-13C,d4
    Inhibitor
    Artemisinin-13C,d4 is 13C and deuterated labeled Artemisinin (HY-B0094). Artemisinin (Qinghaosu), a sesquiterpene lactone, is an anti-malarial agent isolated from the aerial parts of Artemisia annua L. plants. Artemisinin inhibits AKT signaling pathway by decreasing pAKT in a dose-dependent manner. Artemisinin reduces cancer cell proliferation, migration, invasion, tumorigenesis and metastasis and has neuroprotective effects.
    Artemisinin-<sup>13</sup>C,d<sub>4</sub>
  • HY-N0531
    Filixic acid ABA
    Inhibitor
    Filixic acid ABA is a molluscicidal agent against B. peregrina adult snails, with an LD50 of 8.40 ppm. Filixic acid ABA shows 100% mortality of B. peregrina at 15 ppm.
    Filixic acid ABA
  • HY-13582A
    Carbendazim hydrochloride
    Carbendazim hydrochloride is a potent and orally active broad-spectrum?benzimidazole fungicide and can be acts as a pesticide for fungal diseases research, such as Seproria,?Fusarium?and?Sclerotina. Carbendazim hydrochloride is a benzimidazole (HY-Y1825) derivative with antitumor activity and used for cancer research, especially advanced solid tumors and lymphoma.
    Carbendazim hydrochloride
  • HY-N7648
    Atherosperminine
    Inhibitor
    Atherosperminine(Atherospermine)is a nature occurring alkaloid, has antiplasmodial activities in vitro, with an IC50 of 5.80 μM. Atherosperminine is a good reductant with the ability to chelate metals. Atherosperminine has scavenging activity towards the free radical DPPH, with an IC50 of 29.56 µg/mL. Atherosperminine exerts a non-specific relaxant effect on the trachealis.
    Atherosperminine
  • HY-115972
    Anti-Trypanosoma cruzi agent-2
    Inhibitor
    Anti-Trypanosoma cruzi agent-1 (Compd 3b), selective compound against NINOA trypomastigote (IC50 = 0.51 µM) and INC-5 epimastigote form (IC50 = 3.06 µM), posseses anti-T. gondii activity.
    Anti-Trypanosoma cruzi agent-2
  • HY-W019773S
    Albendazole sulfone-d7
    Inhibitor
    Albendazole sulfone-d7 is the deuterium labeled Albendazole sulfone. Albendazole sulfone is a metabolite of Albendazole, and exhibits anti-parasite effect against Echinococcus multilocularis Metacestodes[1][2].
    Albendazole sulfone-d<sub>7</sub>
  • HY-N1667
    2',4'-Dihydroxy-6'-Methoxyacetophenone
    Inhibitor 99.58%
    2',4'-Dihydroxy-6'-Methoxyacetophenone is a phenolic acetophenone from Artemisia annua. Artemisia annua is an analog of Artemisinin that is effective in the research of malaria.
    2',4'-Dihydroxy-6'-Methoxyacetophenone
  • HY-P3361
    IDR-1018
    Inhibitor
    IDR-1018 is an innate defense regulator conjugate, with MICs of 16 μg/mL for MRSA USA300 LAC, MRSA SAP 0017 and S. epidermidis ATCC14990. IDR-1018 can be used to synthesis V-IDR1018 (vancomycin-innate defense regulator conjugate).
    IDR-1018
  • HY-115725
    Antileishmanial agent-1
    Inhibitor
    Antileishmanial agent-1 exhibits the activity against L. amazonensis promastigotes (IC50 = 15.52 μM) and intracellular amastigotes (IC50 = 4.10 μM).
    Antileishmanial agent-1
  • HY-N3754
    Dihydropinosylvin monomethyl ether
    Inhibitor
    Dihydropinosylvin monomethyl ether is a natrual compound with nematicidal activity. Dihydropinosylvin monomethyl ether can inhibit pine wood nematodes infection.
    Dihydropinosylvin monomethyl ether
  • HY-B2066R
    Clofentezine (Standard)
    Inhibitor
    Clofentezine (Standard) is the analytical standard of Clofentezine. This product is intended for research and analytical applications. Clofentezine is a growth inhibitor that is highly lethal to mites.
    Clofentezine (Standard)
  • HY-B1120S
    Temephos-d12
    Temephos-d12 is the deuterium labeled Temephos[1]. Temefos is an organophosphate larvicide, used to treat water infested with disease-carrying insects including mosquitoes, midges, and black fly larvae. Temefos affects the central nervous system through inhibition of cholinesterase, results in death before reaching the adult stage[2][3].
    Temephos-d<sub>12</sub>
  • HY-149956
    Antileishmanial agent-15
    Inhibitor
    Antileishmanial agent-15 (compound 13c) is a potent antileishmanial agent. Antileishmanial agent-15 shows antileishmanial and cytotoxic activity against L. major promastigotes and amastigotes, with IC50 values of 0.78 and 0.99 μM, respectively.
    Antileishmanial agent-15
  • HY-13685S1
    Miltefosine-d4
    Miltefosine-d4 (HePC-d4) is deuterium labeled Miltefosine. Miltefosine is a broad spectrum antimicrobial, anti-leishmanial, phospholipid agent acting by inhibiting the PI3K/Akt activity. Miltefosine is an inhibitor of CTP-phosphocholine cytidyltransferase (CCT).
    Miltefosine-d<sub>4</sub>
  • HY-147806
    Antiparasitic agent-8
    Inhibitor
    Antiparasitic agent-8 (Compound 9) is an antiparasitic agent against Hymenolepis nana with low cytotoxicity.
    Antiparasitic agent-8
  • HY-N2802
    Euptox A
    Inhibitor
    Euptox A (9-Oxo-10, 11-dehydroageraphorone), a cadenine sesquiterpene, is the main toxin that can be isolated from Eupatorium adenophorum. Euptox A induces apoptosis by improving the gene expression level of apoptotic proteases such as caspase-10 in HeLa cells.
    Euptox A
  • HY-110137A
    Furamidine
    Inhibitor
    Furamidine (DB75) is a selective protein arginine methyltransferase 1 (PRMT1) inhibitor with an IC50 of 9.4 μM. Furamidine is selective for PRMT1 over PRMT5, PRMT6, and PRMT4 (CARM1) (IC50s of 166 µM, 283 µM, and >400 µM, respectively). Furamidine is a potent, reversible and competitive tyrosyl-DNA phosphodiesterase 1 (TDP-1) inhibitor. Inhibition of TDP-1 by Furamidine is effective both with single- and double-stranded DNA substrates but is slightly stronger with the duplex DNA. Furamidine is also an antiparasite agent.
    Furamidine
  • HY-151470
    Chitinase-IN-5
    Inhibitor
    Chitinase-IN-5 (8i) is a potent chitinase OfChi-h inhibitor with an IC50 value of 0.051 μM. Chitinase-IN-5 shows good insecticidal activity, it can be used for the research of green pest control and management.
    Chitinase-IN-5

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